Deviation

Definition:
Deviation is a departure from approved procedure or specification.
A deviation is an activity performed differently and/or modified than that specified in an approved document.
There are two types of deviations
1) Planned Deviation.
2) Unplanned Deviation.

1) Planned Deviation -
Planned deviations, which are described, and pre-approved deviation from the current operational document/system, covering a specified period of time or number of batches.

Planned deviation shall be approved before execution

2) Unplanned Deviation -
Unplanned deviations also called as incident.
Incident can be defined as unplanned or uncontrolledevent in the form of non-compliance from the designed systems or procedures at any stage of manufacturing, packaging, testing, holding and storage of drug product due to system failure or equipment breakdown or manual error.



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