Definition:
Solid dispersion is a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug.
-Matrix can be either crystalline or amorphous
-The drug can be dispersed molecularly
-Amorphous particles (clusters)
-Crystalline particles.
-The molecular arrangement governs the properties of solid dispersion
Solid dispersion are prepared:
-To improve drug solubility
-To improve drug stability
-To mask the bitter taste of drug
-To obtain required release profile
-To dispense liquid or gaseous compounds
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