Composition of transdermal patches

Transdermal dermal patches are consist of several component.

The common composition includes the following :

-Backing film

-Release Liner

-Pressure –sensitive adhesive

-Active ingredient  

-Permeation enhancer

-Other additives

-Micro porous or semi permeable membranes

-Pouching materials

Backing films:

Backing films play a critical role in the TDDS as well as during the use of the system.

To protect the active layer and safeguard the stability of the system.

Release liner:

A release liner is a film covered with an anti-adherent coating. To protect the system as long as it is packaged, and it is removed just before the adhesion of the TDDS to the skin.

Pressure –sensitive adhesive :

Serving the matrix that the carrier everything active additive and permeation enhancer.

Active ingredient  :

Are the main ingredients which have a potential impact on the body.

Microporous or semi-permeable membranes:

The porous membrane is a special kind of plastic film which is used in all liquid reservoir patches and in some matrix patches.

Pouching materials:

Most of the patches for use in a TDDS are packaged as unit doses in sealed pouches.The pouching material is therefore critical to the stability and integrity of the product.


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