Peripheral Protein:plasma membrane


-Peripheral proteins are the protein which interacts with the surface of the bilayer membrane but it does not embedded with the membrane. Peripheral protein.

-Peripheral protein loosely attach with the polar head of the membrane lipids at the inner or outer surface of the membrane.

-Peripheral protein may attach integral peripheral protein or slightly penetrate to peripheral region of the lipid bilayer .peripheral protein  can separate from the cell membrane without the rupturing of the cell membrane structure.
-only available on the surface of the plasma membrane.

-Many peripheral proteins are also a part of many complex biochemical pathways. They can be involved in moving substances within or outside of a cell, activate other proteins and enzymes, or be involved in cell to cell interactions.

Function
-Peripheral protein act as enzyme, receptor, catalyze provide the support.
G-proteins and certain protein kinases, interact with transmembrane proteins and the lipid bilayer simultaneously.

-Some polypeptide hormones, antimicrobial peptides, and neurotoxins accumulate at the membrane surface prior to locating and interacting with their cell surface receptor targets, which may themselves be peripheral membrane.

-Peripheral molecule help to hydrophobic molecule to transfer. It act as carrier glycolipid transport protein, oxysterol binding protein.

-These proteins are involved in electron transport chains. They include cytochrome c, cupredoxins, high potential iron protein, adrenodoxin reductase, some flavoproteins, and others.

-Peripheral protein also acts as Hormone and the enzyme.

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