Integral Protein VS peripheral Protein

The differences between the integral membrane protein and the peripheral protein are in their function, location, and the nature of interaction with the lipid bilayer.

Following are the main difference between Integral Protein and peripheral Protein.

	Integral Protein	Peripheral Protein
Location	Integral protein is embedded into or through the cell membrane	Peripheral protein is only located in the inner or outer surface of the phospholipid bilayer like an iceberg
	Integral protein tightly embedded in plasma membrane	Peripheral protein are not tightly embedded in plasma membrane.
Removal	Integral protein is not easily removed from plasma membrane.	Peripheral protein can easily remove from the plasma membrane.
Percentage of protein	It about 70% of the total plasma protein	It about 30% of plasma membrane.
Known as	Intrinsic  protein	extrinsic proteins
Example	Insulin receptor, ion Chanel, gap junction protein	Polypeptide hormones