Definition of Biodegradable polymers:
Biodegradable polymers are defined as polymers comprised of monomers linked to one another through functional group and have unstable linkage in the backbone which degrades by the biological enzyme.
Advantages of biodegradable polymers:
- It provides the drug at a constant controlled rate owes a prescribed period of time.
- The polymers carrier would degrade into nontoxic, absorbable subunits which would be subsequently metabolized.
- The system would be biocompatible would not exhibit dose dumping at any time and polymer would retain its characteristic until after depletion of the drug.
- The degradable system eliminates the necessity for surgical removal of the implanted device following depletion of the drug.
Disadvantages of biodegradable polymers:
- Sometimes the degradable polymers exhibit substantial dose dumping at some point following implantation.
- A degradable system which is administered by injection of a particulate form is non-retrievable.
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